Helle Krogh Johansen Selected Research

Anti-Bacterial Agents (Antibiotics)

3/2024	Mutations in the efflux pump regulator MexZ shift tissue colonization by Pseudomonas aeruginosa to a state of antibiotic tolerance.
8/2023	Antimicrobial resistance of Pseudomonas aeruginosa in a cystic fibrosis population after introduction of a novel cephalosporin/β-lactamase inhibitor combination.
1/2023	The small non-coding RNA B11 regulates multiple facets of Mycobacterium abscessus virulence.
11/2022	New concepts in antimicrobial resistance in cystic fibrosis respiratory infections.
3/2022	Persistent Bacterial Infections, Antibiotic Treatment Failure, and Microbial Adaptive Evolution.
1/2022	Use of inhaled antibiotics among Danish patients with cystic fibrosis.
1/2022	Inter-species interactions alter antibiotic efficacy in bacterial communities.
1/2021	Compensatory evolution of Pseudomonas aeruginosa's slow growth phenotype suggests mechanisms of adaptation in cystic fibrosis.
1/2021	Omics-based tracking of Pseudomonas aeruginosa persistence in "eradicated" cystic fibrosis patients.
12/2020	Bacterial persisters in long-term infection: Emergence and fitness in a complex host environment.

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Helle Krogh Johansen Research Topics

Disease

30	Infections 03/2024 - 05/2004
29	Cystic Fibrosis (Mucoviscidosis) 08/2023 - 04/2005
7	Persistent Infection 03/2022 - 11/2003
6	Neoplasms (Cancer) 09/2014 - 01/2006
5	Neutropenia 09/2014 - 01/2006
5	Mycoses (Diseases, Fungus) 09/2014 - 02/2014
4	Lung Diseases (Lung Disease) 09/2016 - 11/2003
4	Invasive Fungal Infections 09/2014 - 02/2014
3	Pseudomonas Infections 12/2022 - 11/2022
3	Inborn Genetic Diseases (Disease, Hereditary) 08/2015 - 10/2008
3	Wounds and Injuries (Trauma) 07/2015 - 05/2006
2	Respiratory Tract Infections (Respiratory Tract Infection) 05/2021 - 05/2006
2	Osteomyelitis 01/2017 - 02/2013
2	Cross Infection (Nosocomial Infection) 09/2016 - 09/2008
2	Candidiasis (Moniliasis) 11/2015 - 09/2014
2	Inflammation (Inflammations) 03/2015 - 12/2012
1	Brain Injuries (Brain Injury) 03/2024
1	Pneumonia (Pneumonitis) 01/2023
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2023
1	Traumatic Brain Injuries (Traumatic Brain Injury) 04/2022
1	Bacterial Infections (Bacterial Infection) 03/2022
1	Atopic Dermatitis (Atopic Eczema) 01/2022
1	COVID-19 05/2021
1	Candidemia 01/2018
1	Ciliary Motility Disorders (Primary Ciliary Dyskinesia) 01/2015
1	Acquired Immunodeficiency Syndrome (AIDS) 09/2014
1	Critical Illness (Critically Ill) 09/2014
1	Fever of Unknown Origin 02/2014
1	Aspergillosis 02/2014
1	Fibrosis (Cirrhosis) 02/2014
1	Sinusitis 01/2013
1	Bacteremia 09/2011
1	Fungemia 01/2011
1	Burns 05/2006
1	Sepsis (Septicemia) 05/2006

Drug/Important Bio-Agent (IBA)

19	Anti-Bacterial Agents (Antibiotics)IBA 03/2024 - 10/2007
7	Fluconazole (Zonal)FDA LinkGeneric 09/2014 - 01/2006
6	Amphotericin B (Amphotericin)FDA LinkGeneric 09/2014 - 01/2006
3	AzolesIBA 01/2020 - 01/2011
3	Biomarkers (Surrogate Marker)IBA 08/2018 - 01/2016
3	vaccinIBA 08/2015 - 10/2008
3	VaccinesIBA 08/2015 - 10/2008
3	AlginatesIBA 06/2010 - 04/2005
2	AminoglycosidesIBA 03/2024 - 01/2018
2	MacrolidesIBA 12/2022 - 12/2022
2	Ribosomal Proteins (Ribosomal Protein)IBA 12/2022 - 12/2022
2	Niclosamide FDA Link 01/2022 - 05/2021
2	Secretory Immunoglobulin A (SIgA)IBA 08/2018 - 12/2012
2	Immunoglobulin A (IgA)IBA 08/2018 - 01/2013
2	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2015 - 07/2010
2	Voriconazole (Vfend)FDA LinkGeneric 09/2014 - 02/2014
2	liposomal amphotericin B FDA Link 09/2014 - 02/2014
2	Polymyxins (Polymyxin)IBA 05/2013 - 12/2011
2	Colistin (Coly-Mycin)FDA Link 12/2011 - 09/2008
2	Virulence Factors (Pathogenicity Factors)IBA 10/2007 - 05/2007
2	AntibodiesIBA 05/2006 - 11/2003
1	Tobramycin (Nebcin)FDA LinkGeneric 03/2024
1	Cephalosporins (Cephalosporin Antibiotics)IBA 08/2023
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2023
1	Genetic Markers (Genetic Marker)IBA 03/2022
1	Antiviral Agents (Antivirals)IBA 05/2021
1	PyocyanineIBA 01/2020
1	IronIBA 12/2018
1	FluoroquinolonesIBA 01/2018
1	EchinocandinsIBA 01/2018
1	Hydrogen Cyanide (Zyklon B)IBA 01/2017
1	SteroidsIBA 01/2017
1	Bacteriocins (Lantibiotics)IBA 09/2015
1	PyocinsIBA 09/2015
1	Acetic Acid (Vinegar)FDA LinkGeneric 07/2015
1	Acetylcysteine (Siran)FDA LinkGeneric 03/2015
1	AntioxidantsIBA 03/2015
1	Itraconazole (Sporanox)FDA LinkGeneric 09/2014
1	Nystatin (Mycostatin)FDA LinkGeneric 09/2014
1	Miconazole (Monistat)FDA LinkGeneric 09/2014
1	LipidsIBA 09/2014
1	phospholipid emulsion soybean oil (Intralipid)IBA 09/2014
1	Ketoconazole (Nizoral)FDA LinkGeneric 09/2014
1	CreatinineIBA 09/2014
1	deoxycholate drug combination amphotericin BIBA 02/2014
1	Carbapenems (Carbapenem Antibiotics)IBA 02/2014
1	Immunoglobulin G (IgG)IBA 12/2012
1	Lipid AIBA 12/2011
1	Caspofungin (Cancidas)FDA Link 09/2011
1	Oxygen (Dioxygen)IBA 03/2011
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 07/2010
1	Conjugate VaccinesIBA 05/2006

Therapy/Procedure

13	Therapeutics 03/2024 - 07/2010
2	Ventriculostomy 03/2024 - 04/2022
2	Transplantation 01/2022 - 03/2021
2	Lung Transplantation 03/2021 - 12/2013
2	Knee Prosthesis 01/2017 - 02/2013
2	Drug Therapy (Chemotherapy) 09/2014 - 10/2013
1	Nebulizers and Vaporizers (Inhaler) 01/2023
1	Palliative Care (Palliative Therapy) 11/2015
1	Liver Transplantation 09/2014
1	Stem Cell Transplantation 02/2014
1	Prostheses and Implants (Prosthesis) 02/2013
1	Experimental Implants 02/2013
1	Vascular Access Devices (Arterial Line) 09/2011